I joined Taipale lab in December 2014 at Karolinska Institutet and defended my Ph.D. thesis in May 2020.
Gene expression is a complex dynamic process regulated by many distinct regulatory molecules, including DNA, RNA and proteins. To date, our understanding regarding the mechanism of gene regulation is limited due to insufficient knowledge of regulatory elements, even though sequencing technology has greatly broadened our horizons concerning the gene expression pattern alternation. My interest is to decipher the functional role of non-coding regions (or their products) in the gene regulation process, especially those regulatory elements associated with human diseases. To elucidate their roles may help to explain, at least partly, the mechanism by which gene expression is precisely controlled.